About 10 years ago just before Foxwoods WPT poker room opened up, I was playing 5/5 NLHE there which was the biggest game. Min buy was $200, no max buy so the monies on the table would vary from $200 to $50,000 LOL.
My memory is fuzzy on what I bought in for, but I'm pretty sure I had $3K to my name for anything non-bill related (plus with my 1st child being recently born, I needed my fun money). Anyways, I DO know that I had every penny of that roll on the table, whether through rebuys or initial buy, and I had it blown up to just over $5K and feeling reeeeeeally good about my game which makes the beat even harder to handle.
I won't go into street by street play, but I had A2 on a 52252 board, get all the monies in against a player I'm familiar with, and watch the other guy table 55. My reaction to this was identical to Mike McDermott losing his $30K. I sat there, floored, while the dealer swept my chips to other guys direction. I got up, walked away shell shocked. It's the only hand in poker history for me where I was truly shell shocked. I found myself walking around Foxwoods hearing NOTHING. No sounds, no faces, just meandering around the card room and the rest of the casino in auto-pilot trying to find my car while my head was in a total void. I've never experienced anything like it and haven't since then.
I had no money left and it was 9pm on a Saturday. I had a 2.5 hour drive home and arrive home around midnight. I walk in and notice my judgmental sister in law was visiting from Brooklyn (she was pre kids, just out of NYU and knew it all). My wife goes "what are you doing home?" since I normally get home around 9am from casino sessions. I say "I just lost 5 thousand dollars in one hand". They are both on the couch and just look away from me without a sound. I didn't sleep, I kept playing that hand OVER and OVER and OVER. I thought hands like that were impossible at the time and had the guy on AA-KK only, due to preflop action and his amazing tight-ass-aments. Anyways, that single hand has made me call vs raise on many casino rivers since then. Me not having poker money is like normal people not having oxygen. That was a rough time.