Works better for cash games than tournaments, since players are never too short to post and still have chips to play.
I started our NLHE-only crowd out with HORSE, which introduced limit poker, Omaha, Razz, Stud, and hi/lo split-pot games all in a single swift blow. That transitioned to individual tournaments of each type, and eventually ran full league seasons of mixed limit games.
Most popular was the HORS league (NLHE, PLO8, Razz, Stud8) - three tournaments of each game, with the Championship game a rotating format of all four (which is a solid stand-alone tourney format).