Good explanation. I think I like this idea, and probably actually prefer this design spacing it for non aligned edge spots. (Without the explanation it might not have made sense, but it makes sense!) And the chips look good too.
I'll second the comment about not having the 500 denom in purple for just the one denom. I'd prefer either they all should all be slightly different colors to match the denoms/edge spots (which might be tricky with lighter colors, like day green or yellow) or the denom should be the same color, black or red.
^ These. I'd try make sure the white lettering on the dark chips stands out and is just as legible as the black lettering on the lighter chips. The white font will just be areas of the white ceramic not printed/not inked, correct(?), so it may come out different than the black font printed on the white ceramic. Just a wild a** guess, but you might need the white font to be thicker than the black font for both of them to turn out looking the same once the chips are printed.