No big deal. After the first hand, the stacks aren't equal any way. Get the lower denoms in play. That is why you have them. MOAR!That depends on your level of OCD!
Personally I don't have a problem with having different breakdowns in the startingstacks, but some do. However, if it means getting more highly needed lower denom chips in play, then IMO playability trumps equal starting stacks, even if that makes your OCD itch.