My wife and her sister are incredibly bad at geography. We have lived in the same city for 20 years but she still needs explicit directions to get to many places in our area. I try and make it simple, like - we get off the highway at University Ave and she still has to ask, University Ave E or University Ave W. Well, if you go E, it pretty much is farmland and if you go West, the city is - right there - beside the highway. But after all this time she still doesn't get which way is the city that holds 150,000 people.
Anyways, about 20 years back, she and her sister were going to visit my other sister-in-law who just had a baby. So off they go together. Now she lives about 100 km away (like 60 mi). To get there you take an E/W running highway. But her highway exit was closed for construction. So they were told to get off at the exit before and take the service road to the next exit. Which is pretty simple right? So they travel together a couple times uneventfully and now I am going with my wife to see the baby. So we get off at the exit before, she turns onto the North service road but turns the wrong way. I'm like "Honey you are going the wrong way". She insists "No we were given instructions - this is right. My sister and I did this before and it worked". I sat there stunned as she proceeded to drive back one exit, turn, drive over the highway onto the South service road, turn now in the correct direction, pass the same exit again, but on the South side, and eventually reach the correct overpass to my sister-in-laws house. She proudly exclaimed "see it works!". No amount of explaining could convince her of what she was doing. Not only did she follow this route twice before - but her sister was with her and never saw anything wrong with it either!