Option B for the spot patterns.
I'd be concerned about dirty stacks and pots with the red T100 and brown T500 and the T500 and the orange T5000. I'd change the T500 completely to a more traditional purple T500 and go with a green T100, white T100000.
As I have colour blindness I will have to say brown and red look like 2 shade of same colour, it will be a lot of dirty stack for colour blindness chipperI think brown won't be a problem. But you are right that the red and the neon organge are much closer in bad light. I will rework these chips. Thanks for your input.
PS: the 5k chip and the 25k will be 43mm (100 - 1k 39mm) if I go with option B)