The 72 game is great. I think 2bb pay out is good, and it shouldn't change strategy much. Once you start making it a 4-5bb payout, it can get crazy, especially when some people are short stacked. I've definitely blasted off some bluffs with 72. It can make for some interesting calling and bluffing spots. Especially in a home game, everyone loves to see a stone cold bluff flipped over.
I can't find much on strategy advice, but only how I think about it. We play 72o not 72s. I don't 3 bet 72 everytime, unless I am short, then I might just jam it over opens, because winning 32bb on top of taking down the pot, with a 50bb stack. I don't know the odds or the correct solution, but, my home game is very loose pre. That also means I am doing that aggressive jamming strat with my strong premiums as well.
I will flat with 72, and sometimes fold pre when there's action before me that indicates strength, especially with calling stations. The bounty is worth more in smaller pots, 3 or 4 betting pre and then running a triple barrel bluff is pure psycho. I have, but it was more for the love of the game. Mix it into as many lines as you can, but steer away from 3 streets because the value goes down as the pot size increases.
If you are always c betting flop on boards you 100% c bet, that's probably fine, but you have to give it up on later streets at times, especially if you already have natural bluffs on those streets. You can't just not bluff your draws and replace it with 72o, because people might figure out you'll never have them when they hit. Counter to that, with smaller pots, 72 doesn't need to get through very often to be profitable. If the pot is 8bb, and you bet 8bb, you stand to win 40bb. If you can get them to fold 16%(8/48) of the time, you are profitable. If you bet 16bb into 8bb, you need them to fold 28%(16/56). Think about this on every street, I think the river is a good spot to 2x pot when it's checked flop and turn.
You can bet pot on flops in small pots with your best hands because of this, if that's the approach you choose. You can always get exploited, but just realize what opponents you are doing this against.
In summary, you have to bluff less with your draws, and mix in 72 into every line you can. If you take sizes that aren't normal with 72, you need to take those same sizes and lines with your strong value. There are 12-16 combos of 72, so mixing it is important, it's easy to overdue with big sizes.
Maybe you don't change your strategy, but when you see someone taking aggressive sizes or lines with 72, ask yourself if they are considering these things.