I like the inlay, but it seems like it's missing "card room", "club", etc. to establish a setting. Not a requirement by any means, but just by looking at the design elements it looks a bit light. Not a problem, just my opinion.
In regards to colors and edge spots. If you look closely you notice that Vegas had not ironed out a color standard by the 50s. It's quite common to find all kinds of colors for the denoms well into the 50's so don't think you have to limit yourself to today's "Vegas colors." It wasn't standard at all.
On spots, I think you have some considerations to make if you want to keep it to the era. In the 1950s 314, 214, 414, and 312 ruled the day. There are a few here and there that did other things, but for sure the red chip and the black chip are out of place.
To get a better feel for the era, I'd suggest looking at
this article about Vegas Casinos in the 1950s. Cross reference the casinos on that list with t
he list at the Chip Guide and you'll get the picture.
I recently did a set based on the 1940's so I made a lot of the same considerations. I decided to keep it true and I love how it turned out. Ultimately, it's your set and if you want to bend the rules a bit, by all means. Whatever makes you happy!